Molecular cytogenetics
[Molekulare Zytogenetik]
EPTIS factsheet 1353428 | Last revision 2025-04-23 | URL: https://www.eptis.bam.de/pts1353428 https://www.eptis.bam.de/pts1353428
| PT provider | ||||||||||||||||
| PT provider | Berufsverband Deutscher Humangenetiker e.V. Berufsverband Deutscher Humangenetiker e.V. | |||||||||||||||
| Based in | Germany | |||||||||||||||
| Language(s) | German, English | |||||||||||||||
| Remarks | The EQA test is administered via www.bvdh-ringversuche.de; please register to get full access to further information. Aim: The EQA test "Molecular Cytogenetics" aims at assuring the quality of laboratories offering the technique of metaphase FISH (= fluorescence in situ hybridization). Based on images of FISH results available online or on samples delivered to the participants, the EQA test wants participants to find an (optional) aberration and that they issue a correct report based on their findings. Procedure: This robin round test is split up in two different exercises, called “Case 1” and “Case 2”. In general, for Case 1 between 10 and 25 images of FISH results are made available online, together with the corresponding clinical case description and including the result of GTG banding, the indication for FISH analysis and the information on the applied probes. As an alternative, every three to five years participants will receive cell suspension of a clinical case which has to be handled and analysed according to the participant’s own standard operation procedures. In addition, in Case 2 participants have to solve a theoretical problem dealing with the appropriate application of the rules of ISCN nomenclature. Method: Based either on the available images or on the received sample, which is to be handled according to the participant’s own SOP, participants in this robin round test are supposed to hand in a report of findings. Additionally, participants have to answer questions or give additional information in an online questionnaire. Criteria: Participants are expected to find the (optional) aberration and to write a correct report of findings. Furthermore, they are supposed to answer correctly the questions of Case 2. The detailed list of criteria is sent out together with each EQA test. Certificate: Participants will obtain a certificate by BVDH e. V. and RiliBÄK after successful participation (valid for two years). | |||||||||||||||
| Keywords | ||||||||||||||||
| Product groups |
Human test material
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| Testing fields |
Medical analysis
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| Technical details | ||||||||||||||||
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| Aims of the PT scheme | ||||||||||||||||
| Target group of participants | Laboratories which offer metaphase FISH analysis. No geographical restrictions to participation, as long as delivery of the sample within 4 days max is possible. | |||||||||||||||
| Linked to specific legislation / standards | ||||||||||||||||
| Additional, subsidiary aims | validation of testing methods | |||||||||||||||
| Number of participants | 60 | |||||||||||||||
| Accredited or otherwise reviewed by a 3rd party |
Accredited by Deutsche Akkreditierungs-Stelle DAkkS on the basis of DIN EN ISO/IEC 17043 Bundesärztekammer (RiliBÄK) |
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| Operation is commissioned / requested by | Bundesärztekammer (RiliBÄK) | |||||||||||||||
| Fees and frequency | ||||||||||||||||
| Participation fee | 400 euros net | |||||||||||||||
| Regularly operated | Yes (Once per year) | |||||||||||||||
| Year of first operation | 1997 | |||||||||||||||
| Contact details of the PT provider | ||||||||||||||||
| Provider | Contact person | |||||||||||||||
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Berufsverband Deutscher Humangenetiker e.V.
Linienstraße 127 10115 Berlin Germany Phone: 030 55954411 Fax: 030 55954414 Web: https://www.bvdh-ringversuche.de https://www.bvdh-ringversuche.de |
Frau Susanne Brandt
Phone: 02403 838054 Fax: Email: brandt@bvdh.de brandt@bvdh.de |
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